Computer-Aided Diagnosis for the Resect and Discard Strategy for Colorectal Polyps: A Systematic Review and Meta-Analysis

Aims According to the Resect and Discard strategy, endoscopists can replace post-polypectomy pathology with real-time prediction (optical diagnosis) of polyp histology during colonoscopy. This strategy is only applicable to small polyps≤5mm and if the endoscopist prediction was made with high confidence. The variability in real-time optical diagnosis among different endoscopists can be standardized by the high accuracy expected from computer-aided diagnosis systems (CADx). The aim of this meta-analysis is to provide a preliminary estimate of the accuracy of CADx and to assess its effect in clinical practice.