材料科学
自愈
热电效应
自愈材料
伤口愈合
纳米技术
热电材料
生物医学工程
机械工程
复合材料
医学
热导率
外科
工程类
热力学
物理
病理
替代医学
作者
Yuwei Zhang,Bangzhi Ge,Jianghe Feng,Nianling Kuang,Haolin Ye,Zhenyu Yuan,Mingjie Wu,Binbin Jiang,Juan Li,Qiang Sun,Lin Niu,Minhao Zhu,Yadong Xu,Jie Wang,Ruiheng Liu,Shaojie Dong,Chongjian Zhou
标识
DOI:10.1002/adfm.202403990
摘要
Abstract Electric signal accelerates full‐thickness wound healing in the clinic, which is usually generated by a large power generation system and requires delicate control by authorized personnel. Here, a self‐powered flexible and biocompatible thermoelectric device with exceptionally high power generation efficiency is developed. It generates 10 mV voltage at a temperature gradient of 10 K, outperforming all reported flexible thermoelectric devices. Accordingly, it can directly and efficiently convert the omnipresent heat in the skin to electricity at the microvolt level. The output electricity activates and upregulates the expression of Piezo1‐mediated pathways that are associated with tissue regeneration, accelerating the cell migration and proliferation in vitro and healing the wound 4 days faster in vivo. Importantly, the thermoelectric device fast‐heals the wound without involving any additional electric circuit such as an amplifier. These advantages will revolutionize the designing of self‐powered wearable bioelectronics for diagnosing, monitoring, and treating various pathological conditions employing the skin heat.
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