环状RNA
生物
计算生物学
功能(生物学)
生物标志物
核糖核酸
非编码RNA
生物信息学
遗传学
基因
出处
期刊:Epigenomics
[Future Medicine]
日期:2023-06-01
卷期号:15 (12): 677-685
被引量:26
标识
DOI:10.2217/epi-2023-0141
摘要
circRNA is a type of RNA molecule with a circular structure. From initially thinking it was useless to now discovering that it has important and complex functions, the importance of circRNA is increasingly being recognized. circRNA was first discovered as an ncRNA with a molecular sponge function. Clinically, due to its special molecular structure, researchers are generally interested in its potential as a biomarker. Recently, circRNA has been proven to have many functions other than encoding proteins. In the clinical setting, circRNA also has strong potential for application in vaccine preparation and targeted therapy. This article discusses the synthesis of circRNA, introduces its functions and discusses its future development prospects.
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