氧化应激
蛋白激酶B
细胞凋亡
再灌注损伤
药理学
医学
缺血
PI3K/AKT/mTOR通路
化学
内科学
生物化学
作者
Mingyue Duan,Ning Yu,Jia Liu,Yang Zhao,Jing Zhang,Siyi Song,Shi-Lei Wang
摘要
This study demonstrates that remimazolam activates the AKT/GSK-3β/NRF2 pathway, thereby attenuating oxidative stress and apoptosis to protect against brain I/R injury.
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