High-sensitivity and stability electrochemical sensors for chlorogenic acid detection based on optimally engineered nanomaterials

Developing cost-effective and efficient analytical methods is essential for detecting chlorogenic acid (CGA), as excessive consumption of CGA, despite its significant antioxidant, anticancer, and anti-inflammatory properties, can cause serious health problems. The remarkable progress and adjustable features of nanomaterials have significantly improved the analytical capabilities of electrochemical sensors for CGA. This review examines the use of optimally engineered nanomaterials in CGA electrochemical sensors, emphasizing the design and modification strategies of various nanomaterials. It starts with an introduction to the basic principles of electrochemical sensors, detailing their components and the analytical methods employed. Subsequently, the review explores how structural and compositional adjustments in electrocatalysts from different nanomaterial categories enhance CGA detection performance. In conclusion, it discusses the challenges and opportunities linked to designing nanomaterials for modified electrodes in CGA sensors. This review seeks to enhance the understanding of the connection between nanomaterial structures and the performance of CGA electrochemical sensors, offering new perspectives for the future design of highly efficient CGA electrochemical sensors.