Construction of Nitrogen-Containing Three-Dimensional Frameworks via Formation and Cycloaddition of endo-Cyclic Azomethine Ylide

Triggered by the reaction of an oxime ether with a rhodium carbenoid, nitrogen-containing three-dimensional frameworks were constructed from linear motifs via the intramolecular cycloaddition of endo-cyclic azomethine ylide. In this transformation, successive stereocenters containing quaternary carbons were formed, affording the corresponding tricyclic compounds in moderate-to-good yields. The utility of these products was demonstrated through several transformations.