Palladium-Catalyzed Cascade Synthesis of Tricyclic Quinolin-2(1H)-ones from 1,7-Enynes and Hydroxylamines

A palladium-catalyzed cascade radical cyclization and C-H amination of 1,7-enynes with perfluoroalkyl iodides and hydroxylamine has been developed for the rapid construction of tricyclic quinolin-2(1H)-one scaffolds. The reaction proceeded smoothly...