Imaging of Microtubules in a Nonhuman Primate Model of Alcohol Use Disorder

C]MPC-6827 uptake across multiple brain regions, particularly in the amygdala, globus pallidus, and substantia innominata. Statistically significant reductions in tracer uptake were observed in early scan windows (15 and 30 min), suggesting compromised MT integrity due to chronic EtOH SA. These findings provide compelling evidence that chronic alcohol consumption induces significant changes in microtubule dynamics, potentially contributing to pathological processes underlying AUD.