ROS-Sensitive MgOSiO2 Nano Capsules for Effective Against Osteoarthritis in Rat Model

As a multi-functional ROS-responsive nanosystem, MgO@SiO₂ nano capsules not only slow the release of MgO NPs and reduce their cytotoxicity but also reduce ROS production and thus lessen the inflammatory response in cartilage. This dual-action mechanism achieves therapeutic efficacy for osteoarthritis, offering a promising strategy to delay or reverse osteoarthritis progression.