医学
代谢综合征
斯科普斯
腹部肥胖
肥胖
糖尿病
内科学
疾病
2型糖尿病
冠状动脉疾病
心脏病学
梅德林
内分泌学
政治学
法学
作者
Ofer Kobo,Ronit Leiba,Ophir Avizohar,Amir Karban
标识
DOI:10.1016/j.ejim.2019.03.002
摘要
Obesity is a recognized risk factor for various cardio-metabolic diseases and several indices are used clinically to assess overall cardio-metabolic risk [ [1] Langenberg C. Sharp S.J. Schulze M.B. Rolandsson O. Overved K. et al. Long-term risk of incident type 2 diabetes and measures of overall and regional obesity: the EPIC-InterAct casecohort study. PLoS Med. 2012; 9 ([Epub 2012 Jun 5])e1001230https://doi.org/10.1371/journal.pmed.1001230 Crossref PubMed Scopus (145) Google Scholar ]. The metabolic syndrome, which is an independent risk factor for coronary heart disease, peripheral artery disease, stroke and total mortality [ 2 Athyros Vasilios G. Ganotakis Emmanuel S. Elisaf Moses S. Liberopoulos Evangelos N. Goudevenos Ioannis A. Karagiannis Asterios Prevalence of vascular disease in metabolic syndrome using three proposed definitions. Int J Cardiol. Apr 25, 2007; 117 ([Epub 2006 Jul 18]): 204-210 Abstract Full Text Full Text PDF PubMed Scopus (84) Google Scholar , 3 Alexander Charles M. Landsman Pamela B. Teutsch Steven M. Haffner Steven M. NCEP-defined metabolic syndrome, diabetes,and prevalence of coronary heart disease among NHANES III participants age 50 years and older. Diabetes. May, 2003; 52: 1210-1214 Crossref PubMed Scopus (1258) Google Scholar , 4 Malik Shaista Wong Nathan D. Franklin Stanley S. Kamath Tripthi V. L'Italien Gilbert J. Pio Jose R. et al. Impact of the metabolic syndrome on mortality from coronary heart disease, cardiovascular disease, and all causes in United States adults. Circulation. 2004; 110: 1245-1250 Crossref PubMed Scopus (1418) Google Scholar , 5 Scuteri A. Najjar S.S. Morrell C.H. Lakatta E.G. The metabolic syndrome in older individuals: prevalence and prediction of cardiovascular events: the cardiovascular health study. Diabetes Care. Apr, 2005; 28: 882-887 Crossref PubMed Scopus (247) Google Scholar ], was defined by the Adult Treatment Panel III (ATP III) as at least three of the five conditions – central obesity (as defined by men waist circumference > 40 in. or women waist circumference > 35 in.), raised triglycerides (above 150 mg/DL or on treatment), reduce HDL (below 40 mg/DL for men or 50 mg/DL for women), raised blood pressure (above 130/85mmHG or on treatment) and abnormal fasting plasma glucose (above 110 mg/DL or on treatment) [ [6] National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) Third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III). Final report. Circulation. 2002; 106: 3143-3421 Crossref PubMed Scopus (11271) Google Scholar ].
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