材料科学
光电流
光电子学
电子转移
化学工程
电化学
电极
氧化还原
可见光谱
作者
Jun-Tao Cao,Bing Wang,Yu-Xiang Dong,Qian Wang,Shu-Wei Ren,Yan-Ming Liu,Wei-Wei Zhao
出处
期刊:ACS Sensors
[American Chemical Society]
日期:2018-05-31
卷期号:3 (6): 1087-1092
被引量:38
标识
DOI:10.1021/acssensors.8b00332
摘要
This work reports the elegant bridging of enzymatic generation of electron donor with photogenerated hole-induced chemical redox cycling amplification (RCA) for innovative photoelectrochemical (PEC) immunoassay, by the aid of a heterojunction photoelectrode with split-type strategy. Specifically, the system was exemplified by the alkaline phosphatase (ALP) catalytic generation of ascorbic acid (AA), the redox cycling of AA by tris (2-carboxyethyl) phosphine (TCEP) as reductant, and the use of a novel Bi2S3/Bi2Sn2O7 heterojunction and myoglobin (Myo) as the photoelectrode and the target, respectively. After the immunoreaction and ALP-induced production of AA, the subsequent oxidation of AA by the photogenerated holes of the Bi2S3/Bi2Sn2O7 heterojunction could be cycled via the regeneration of AA by TCEP from the oxidized product of dehydroascorbic acid, leading to easy signal amplification for the sensitive immunoassay of Myo in real samples. It is believed that this work provided a basis for further desig...
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