Objective:To evaluate the effects of individualized hemodialysis on lowering the hemodialysis complications.Methods:All together312times of hemodialysis in20chronic renal failure patients were investiˉgated.The clinical effects of two different dialysis methods which included routine dialysis and individualized dialysis were compared.Results:There were a few influences on plasma osmotic pressure and serum natrium in individualized hemodialysis group with good effects and fewer complications.Conclusion:Individualized dialysis could effectively prevent the dialysis complications,promote the dialysis quality together with ensuring the dialysis effects.