SMARCA4-deficient Non-small Cell Lung Carcinoma Harboring ALK Fusion

SMARCA4 -deficient non-small cell lung cancers are usually of poor prognosis and associated with smoking-related mutations. Here, we report the case of a SMARCA4 -deficient non-small cell lung cancer (NSCLC) occurring in a non-smoker female and harboring ALK fusion. Our case highlights for physicians to be especially cautious with molecular biological results in case of SMARCA4 -deficient non-small cell lung cancer occurring in nonsmokers.