Palladium-catalyzed double strain-release (3+3) cycloaddition for the synthesis of vinylbicyclo[3.1.1]heptanes

All-carbon bicyclo[3.1.1]heptanes are important structural motifs in bioactive compounds and serve as bioisosteres for substituted benzenes. However, their synthesis, especially through polar (3+3) cycloaddition strategies, remains underexplored. Herein, we present...