中性粒细胞胞外陷阱
肝素
中性粒细胞弹性蛋白酶
中和
弹性蛋白酶
化学
细胞外
蛋白水解酶
生物化学
免疫学
酶
医学
炎症
抗体
作者
Joram Huckriede,Gwen M Keulen,Marcel C.G. van de Poll,Kanin Wichapong,Chris Reutelingsperger,Gerry A. F. Nicolaes
标识
DOI：10.1016/j.jtha.2025.03.039
摘要
NE can proteolyze extracellular histones, resulting in reduced cytotoxicity and inflammation in vitro. Histone proteolysis can be enhanced by the addition of heparins, indicating a potential combinatory treatment of histone-mediated events by heparins and NE in acute inflammatory diseases.
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(2025-6-4)
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