Surface Enhanced Raman Spectroscopic (SERS) detection of antibiotics and metabolites in complex biological matrices

The potential of surface enhanced Raman spectroscopy (SERS) in bioanalytics is illustrated by the example for detecting the antibiotic ciprofloxacin in pharmaceutical formulations in its relevant concentrations. Both, Raman and SERS spectroscopy are applied to identify the target analyte dependent on the complexity of the matrices.