化学
光热治疗
适体
纳米技术
纳米颗粒
双模
材料科学
遗传学
生物
工程类
航空航天工程
作者
Lixia Su,Bingqian Liu,Yonghuan Su,Dianping Tang
出处
期刊:Talanta
[Elsevier]
日期:2023-08-01
卷期号:260: 124629-124629
标识
DOI:10.1016/j.talanta.2023.124629
摘要
In this study, we developed a simultaneous readout of pressure and temperature dual-signals platform based on the second near-infrared (NIR II) light response-based polydopamine (PDA)-functionalized-AuPt nanoparticles (NPs)@CuS nanosheets (PDA/AuPt@CuS NS) composite. Due to the excellent NIR photothermal performance of PDA/AuPt@CuS NS, it contribute to the decomposition of H2O2 and NH4HCO3 to generate gases (including O2, CO2, and NH3) can be promoted, which can amplify the pressure signals in a sealed container. A sandwich mode is formed between Fe3O4 NPs and PDA/AuPt@CuS NS based on the dual-aptamer when target pathogenic bacteria is present. And, it is possible to convert the molecular recognition signals between the dual-aptamers into amplified pressures and temperatures, which can be read out by a portable pressure meter and smartphones simultaneously. It may offer the possibility for quantitative POCT analysis of Pathogenic Bacteria. Moreover, because of the high photothermal efficiency of this method, the developed dual-mode method can achieve that following the detection of bacteria and killing them immediately. As a result, secondary contamination is eliminated and bacterial transmission is avoided. The developed dual-signal sensing platform is also inexpensive, simple to operate and rapidly, indicating that it can be used for food safety analysis, clinical applications, and environmental monitoring.
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