Cyclic Dithiophosphoric Acids in Reactions with (S)-(–)-Nicotine

Cyclic dithiophosphoric acids derived from (2S,3S)-(+)-dimetyl tartrate, 2,3-dihydroxynaphthalene, 2,2'-dihydroxybiphenyl, and racemic 1,1'-bi(2-naphthol) react with (S)-(–)-nicotine to form 5-(pyridine)-1-methylpyrrolydinium dithiophosphates which showed high antimicrobial activity against Bacillus cereus and Candida albicans.