NETSKINMODELS: A European Network for Skin Engineering and Modeling

More than 40 years of research in dermatology has led to the development of advanced skin models, including 3-dimensional (3D) organotypic cultures containing fibroblasts, keratinocytes, melanocytes, immune cells, and sensory cells; skin-on-a-chip models; bioprinted skin; and mathematics-based models, known as in silico computational models. These models are important tools in both fundamental and translational skin research (van den Bogaard et al., 2021). For clinical applications, clinical-grade 3D-reconstructed epidermis autografts can treat extensive burns and genodermatoses after gene correction (De Rosa and De Luca, 2022).