The effect of aerobic exercise on serum IL-4 and TNF-αof patients with allergic rhinitis

Objective:To investigate the effect of aerobic exercise on immune factor IL-4,TNF-αin patients with allergic rhinitis,which provide a theoretical basis for the treatment of allergic rhinitis.Method:Tirty-two allergic rhinitis patients were selected and divided into a control group(14people)and the experimental group(18people).During the treatment,both groups receive conventional symptomatic treatment.Meanwhile,aerobic exercise therapy is applied to the experimental group for 40-60minutes a day,3-4days a week.Serum IL-4,TNF-αand allergic rhinitis symptoms graded scoring were tested before and after 6month therapy.Result:After six months of exercise intervention,the IL-4,and TNF-αlevels of experimental group were significantly lower than the level of control group.The symptoms score is also significantly decreased in experimental group.Conclusion:Aerobic exercise had good therapeutic effect in patients with allergic rhinitis.The mechanism may be that aerobic exercise can reduce the level of IL-4and TNF-α,which can relieve infiltration and activation of inflammatory cells.