神经毒素
肉毒神经毒素
肉毒梭菌
皮肤病科
医学
痤疮
乙酰胆碱
肉毒毒素
胆碱能的
化学
药理学
麻醉
内科学
毒素
生物化学
作者
Nark-Kyoung Rho,Young-Chun Gil
出处
期刊:Toxins
[MDPI AG]
日期:2021-11-19
卷期号:13 (11): 817-817
被引量:14
标识
DOI:10.3390/toxins13110817
摘要
Intradermal injection of botulinum neurotoxin is a frequently performed procedure in aesthetic dermatology to improve facial skin tone, texture, fine wrinkles, and enlarged pores. In practice, botulinum neurotoxin type A is also used to reduce skin oiliness of the face. There is increasing evidence that acetylcholine plays specific roles in sebum production, suggesting that botulinum neurotoxin type A may reduce sebum production by interfering with cholinergic transmission between sebaceous glands and autonomic nerve terminals. Botulinum neurotoxins can also inhibit several pathogenetic components of acne development, suggesting that botulinum neurotoxins can be used as a safe and effective treatment modality for acne and other skin disorders related to overactivity of sebaceous glands. This review aims to explore the current evidence behind the treatment of facial seborrhea and acne with botulinum neurotoxin type A.
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