心力衰竭
姜黄素
医学
射血分数
重症监护医学
人口
内科学
心脏病学
药理学
环境卫生
作者
Amin Saeidinia,Faeze Keihanian,Alexandra E. Butler,Ramin Khameneh Bagheri,Stephen L. Atkin
标识
DOI:10.1016/j.phrs.2018.03.009
摘要
Heart failure is a major public health concern and one of the most common reasons for a cardiac hospital admission. Heart failure may be classified as having a reduced or preserved ejection fraction and its severity is based on the symptom score. Given the aging population, it is predicted that admissions with heart failure will increase. Whilst pharmacological therapy has improved the associated morbidity and mortality, there is a need for additional therapies to improve the clinical outcome as the death rate remains high. Curcumin is a natural product derived from turmeric that appears to have cardiovascular benefit through a number of mechanisms. In this review, we have assessed the mechanisms by which curcumin may exert its effects in different models of heart failure and show that it has promise as a complementary treatment in heart failure.
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