Allergic Rhinitis as a Predictor for Wheezing Onset in School-aged Children

MK Rochat, S Illi, MJ Ege; Multicentre Allergy Study (MAS) Group. J Allergy Clin Immunol. 2010;126(6):1170–1175 To determine if rhinitis in early childhood is an independent predictor of wheezing between the ages of 5 and 13 years. The study followed 1314 healthy children, from birth to the age of 13 years, as part of the German Multicenter Allergy Study. This was a prospective, multicenter birth-cohort study that used standardized questionnaires, interviews, and objective sensitization methods. To better characterize the association between sensitization and rhinitis on the incidence of wheeze, 4 rhinitis phenotypes were …