Study on Reaction Process of Synthesis of Indole from Aniline and Ethylene Glycol

The reaction process of synthesis of indole from aniline and ethylene glycol was studied by GC-MS. Based on experimental results, a new reaction process proposed. It was found to be quite complicated with involvement of a few of main phases: condensation, cyclization, elimination and so on, which provides a theoretical guild for the development of used catalysts. It could be presupposed that the yield of synthesis of indole was related to dehydrogenation activity of catalysts.