[Clinical course and histopathology of acute oliguric and non-oliguric renal insufficiency].

A retrospective analysis of clinical course and hystopathologic lesions of 23 patients with multiple system organ failure (MSOF) showed that: non-oliguric acute renal failure is more frequent than the oliguric one; the prognosis is severe in both forms; hystopathologic findings are similar. Since acute tubular necrosis during sepsis is characterized by an high incidence of microthrombosis, the prophylactic use of heparin could be justified.