Synthesis of 5-Hydroxyoxaindan-2-ones and Indol-5-ols from 1,4-Cyclohexanedione

1,4-Cyclohexanedione reacted with 2-oxocarboxylic acids to give 5-hydroxyoxaindan-2-ones including homogentisic lactone in one pot.The obtained aromatic compounds were transformed into indol-5-01s in a few steps.The sequential reactions showed a significance of 14-cyclohexanedione as a starting material in aromatic synthesis and an alternative access to the indol-5-01s.Synthesis of aromatic compounds is a major goal of organic synthesis and construction of phenolic compounds is an important area because of their utility in various fields.For example, chromans bearing a phenolic hydroxyl group display distinctive biological activity,' cannabinoids contain 1,3-