生物
胚胎干细胞
桑格测序
先证者
外显子组测序
男科
胚胎发生
不育
遗传学
突变
胚胎
医学
基因
怀孕
作者
Jian Mu,Wenjing Wang,Biaobang Chen,Ling Wu,Bin Li,Xiaoyan Mao,Zhihua Zhang,Jing Fu,Yanping Kuang,Xiaoxi Sun,Qiaoli Li,Jin Li,Lin He,Qing Sang,Lei Wang
标识
DOI:10.1136/jmedgenet-2018-105936
摘要
NLRP2 and NLRP5 are novel mutant genes responsible for human early embryonic arrest. This finding provides additional potential diagnostic markers for patients with recurrent failure of ART and helps us to better understand the genetic basis of female infertility characterised by early embryonic arrest.
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