化学
硝基
甲醇
质子核磁共振
乙酰乙酸酯合成
药物化学
立体化学
有机化学
烷基
作者
Russell R. King,Larry A. Calhoun
摘要
N-acetyl-4-nitrotryptophan methyl ester (2), N-acetyl-5-nitrotryptophan methyl ester (3), N-acetyl-6-nitrotryptophan methyl ester (4) and N-acetyl-7-nitrotryptophan methyl ester (5) were synthesized through a modified malonic ester reaction of the appropriate nitrogramine analogs followed by methylation with BF(3)-methanol. Assignments of the (1)H and (13)C NMR chemical shifts were made using a combination of (1)H-(1)H COSY, (1)H-(13)C HETCOR and (1)H-(13)C selective INEPT experiments.
科研通智能强力驱动
Strongly Powered by AbleSci AI