Very Important Publication: Hypoiodite‐Catalyzed Regioselective Oxidation of Alkenes: An Expeditious Access to Aldehydes in Aqueous Micellar Media

Abstract A highly anti‐Markovnikov selective oxidation of alkenes based on in situ generated hypoiodite catalysis in aqueous micellar media under mild conditions has been described. This novel catalytic system realizes an efficient synthesis of aldehydes from alkenes in an economically viable and environmentally safe fashion. The preliminary mechanistic studies suggest that the reaction proceeds via tandem iodofunctionalization/1,2‐aryl or alkyl migration. The scope and limitations of this tandem process are demonstrated with various mono‐ and disubstituted (terminal and internal) olefins. magnified image