Janus Kinase 2 Inhibitors. Synthesis and Characterization of a Novel Polycyclic Azaindole
作者
Tiansheng Wang,John P. Duffy,Jian Wang,Summer Halas,Francesco G. Salituro,Albert C. Pierce,Harmon J. Zuccola,James R. Black,James K. Hogan,Scott Jepson,Dina Shlyakter,Sudipta Mahajan,Yong Gu,Thomas C. Hoock,Mark L. Wood,Brinley F. Furey,J. Daniel Frantz,Lisa M. Dauffenbach,Ursula A. Germann,Bin Fan
The synthesis and characterization of a novel polycyclic azaindole based derivative is disclosed, and its binding to JAK2 is described. The compound is further evaluated for its ability to block the EPO/JAK2 signaling cascade in vitro and in vivo.
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(2025-6-4)
无极微光
学术雷锋
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北白川anko
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DW
秋风
坚强冰枫
乐空思
渡人舟
吃葡萄不吐葡萄皮
v0id
Criminology34
飘逸的大雁
散逸层梦游
Mm11
牧青
Elsevier大王
OK
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