A novel combination (“CHAP”) regimen for management of livedoid vasculopathy in 12 patients

To the Editor: Livedoid vasculopathy (LV) is characterized by recurrent episodes of painful purpuric, ulcerative lesions that heal with porcelain white atrophic scars. The pathophysiology is that of a thrombo-occlusive vasculopathy. 1 Criado P.R. Rivitti E.A. Sotto M.N. deCarvalho J.F. Livedoid vasculopathy as a coagulation disorder. Autoimmun Rev. 2011; 10: 353-360 Crossref PubMed Scopus (55) Google Scholar LV can be associated with an underlying coagulopathy or disorder of fibrinolysis, collagen vascular disease, or paraproteinemia. 2 Alavi A. Hafner J. Dutz J.P. et al. Livedoid vasculopathy: an in-depth analysis using a modified Delphi approach. J Am Acad Dermatol. 2013; 69: 1033-1042 Abstract Full Text Full Text PDF PubMed Scopus (70) Google Scholar