炎症
体内
卡拉胶
藜藜
化学
消炎药
生物化学
生物
免疫学
遗传学
食品科学
作者
Dávia Guimarães Pompeu,Helon Guimarães Cordeiro,Flávia Cristina Policarpo Tonelli,Adriana M. Godin,Ivo S.F. Melo,Tamires C. Matsui,Felipe F. Rodrigues,Jose Antonio da Silva,Márcio de Matos Coelho,Renes R. Machado,Paulo Afonso Granjeiro
标识
DOI:10.1080/14786419.2021.1980791
摘要
Chenopodin is an 11S-type globulin purified from Chenopodium quinoa seeds, which can bind carbohydrates and hemagglutinating human erythrocytes. The present study aimed to evaluate the N-terminal structure of the heterodimeric Chenopodin and its effects in models of inflammation. Chenopodin presented two subunits on its structure and has N-terminal homology with other Chenopodin in 92%. Chenopodin decreased paw edema and neutrophil recruitment induced by carrageenan in mice. Concluding, we demonstrated that Chenopodin exhibits in vivo anti-inflammatory activity.
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