医学
阻塞性睡眠呼吸暂停
持续气道正压
心脏病学
多导睡眠图
心房颤动
血压
麻醉
睡眠呼吸暂停
心力衰竭
内科学
动态血压
呼吸暂停
作者
Joseph A. Diamond,Haisam Ismail
标识
DOI:10.1016/j.cger.2021.04.006
摘要
Obstructive sleep apnea (OSA) presents as repetitive interruptions of ventilation >10 seconds during sleep as a result of upper airway obstruction resulting in increased respiratory effort. Intermittent hypoxia causes physiologic changes resulting in increased catecholamine production, increased total peripheral resistance, tachycardia, and increased venous return, leading to increased cardiac output, hypertension, tachyarrhythmias, left ventricular hypertrophy, and heart failure. OSA causes an abnormal dip on 24-hour ambulatory blood pressure monitoring. Definitive diagnosis is made by polysomnography. Continuous positive airway pressure (CPAP) remains the first-line treatment. Effective treatment using CPAP reduces blood pressure and is indispensable for proper management of atrial fibrillation.
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