Night black shade (Solanum Nigrum) is an important medicinal plant widely used in the Unani system of Medicine. (Family – Solanaceae). The plants are cultivated throughout the country in dry parts. Common in cultivated lands, roadsides and gardens. The plants are prescribed in various aliments like – Ascites, Piles, Chronic Cirrhosis of the liver, Gonorrhoea, Gouty joints, and various skin disorders. Through this paper, the effort has been to collect information on the Medicinal properties of Mako (Solanum Nigrum) plant species.