流行病学
病理生理学
医学
复杂局部疼痛综合征
梅德林
重症监护医学
生物信息学
物理疗法
病理
生物
生物化学
作者
Michael C Ferraro,Neil E O’Connell,Claudia Sommer,Andreas Göebel,Janet H. Bultitude,Aidan G Cashin,G. Lorimer Moseley,James H McAuley
标识
DOI:10.1016/s1474-4422(24)00076-0
摘要
Summary
Complex regional pain syndrome (CRPS) is a rare pain disorder that usually occurs in a limb after trauma. The features of this disorder include severe pain and sensory, autonomic, motor, and trophic abnormalities. Research from the past decade has offered new insights into CRPS epidemiology, pathophysiology, diagnosis, and treatment. Early identification of individuals at high risk of CRPS is improving, with several risk factors established and some others identified in prospective studies during the past 5 years. Better understanding of the pathophysiological mechanisms of CRPS has led to its classification as a chronic primary pain disorder, and subtypes of CRPS have been updated. Procedures for diagnosis have also been clarified. Although effective treatment of CRPS remains a challenge, evidence-based integrated management approaches provide new opportunities to improve patient care. Further advances in diagnosis and treatment of CRPS will require coordinated, international multicentre initiatives.
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