Preliminary Assessment of Intravoxel Incoherent Motion Diffusion-Weighted MRI (IVIM-DWI) Metrics in Normal Brain Tissue

The microstructure and micro-perfusion changes in normal brain aging is barely understand. The objective of this study is to describe these microscopic changes in normal brain tissue by intravoxel incoherent motion diffusion-weighted MRI (IVIM-DWI). Preliminary results show decreased D, D* and increased f in elder subjects compare with the youngers.