医学
单克隆抗体
发病机制
单克隆
肾病
免疫学
抗体
免疫球蛋白A
癌症研究
内分泌学
糖尿病
免疫球蛋白G
作者
Mohit Mathur,Jonathan Barratt,Bobby Chacko,Tak Mao Chan,Laura Kooienga,Kook‐Hwan Oh,Manisha Sahay,Yusuke Suzuki,Muh Geot Wong,Jill Yarbrough,Jing Xia,Brian J.G. Pereira
标识
DOI：10.1056/nejmoa2305635
摘要
A proliferation-inducing ligand (APRIL) is implicated in the pathogenesis of IgA nephropathy. Sibeprenlimab is a humanized IgG2 monoclonal antibody that binds to and neutralizes APRIL.
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