Diagnosis and management of invasive fungal diseases by next-generation sequencing: are we there yet?

Introduction Invasive fungal diseases (IFDs) are a serious threat to immunocompromised patients. Routine diagnostic methods have limited performance in identifying IFDs. Next-generation sequencing (NGS) including metagenomic NGS (mNGS) and whole genome sequencing (WGS) recently emerged as diagnostic methods that could provide more accurate and timely diagnoses and management of IFDs.