巨细胞病毒
间隙
Wiskott-Aldrich综合征
免疫学
脐带血
移植
巨细胞病毒感染
医学
病毒学
人巨细胞病毒
病毒
疱疹病毒科
生物
病毒性疾病
内科学
泌尿科
基因
生物化学
作者
Yongwei Yue,Lijun Meng,Jing Ling,Liyan Fan,Yanlei Zhang,Yixin Hu,Alex H. Chang,Shaoyan Hu
标识
DOI:10.3389/fmed.2022.988847
摘要
NK cells have important functions in resisting cytomegalovirus infection, as they proliferate after viral infection and have certain immunological memory. Here, we report infusion of haploid donor-derived natural killer cells to treat two pediatric patients with Wiskott-Aldrich syndrome (WAS) who were infected with cytomegalovirus after cord blood transplantation (CBT), which successfully cleared the viral infection in both patients.
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