Objective To study the anti-tumor effect of Huai Er,a Chinese prepared medicine,on the cellular immune function.Methods Forty cases of post-operative gastric cancer patients were divided into treatment group and control group randomly.Huai Er and 5-Fu were used respectively.Peripheral blood samples in the 40 patients were collected to detect the lymphocyte subsets during pre-operatively,2 weeks,6 weeks and 10 weeks after operation,respectively.The data were statistically analyzed by paired samples.Results The CD3+,CD3+CD4+,CD3+CD4+/CD3+CD8+,and NK cells increased remarkably 6 weeks and 10 weeks post-operatively compared with 2 weeks post-operatively(P0.05)in treatment group.Conclusions Huai Er may produce some anti-tumor effect by improving cellular immune function.