An autopsy pathological analysis of 63 cases with acute myocardial infarction with or without thrombolysis

AIM To analyze complications of acute myocardial infarction with or without thrombolysis. METHODS 63 cases with acute myocardial infarction (AMI) were examined by autopsy, 26 of whom had undergone thromobolytic therapy and 37 routine treatment. RESULTS The two groups had no difference in sex, age, risk factors of CHD, times and sections of infarction, serum creatine kinase and the narrowing degree of vessels ( P 0.05). The myocardial hemorrhage in non thrombolysis group was much higher than that in thrombolysis group and the cardiac rupture in thrombolysis was also higher than that in non thrombolysis group ( P 0.05 ). CONCLUSION Compared with AMI without thrombolysis, the incidence of cardiac rupture from AMI treated with thrombolysis is higher in the early stage, but not other complications such as single myocardial hemorrhage and infarction size expanding. The hemorrhage and cardiac rupture are associated with the severity of narrowing vessels.