Clinical Features and Pathological Analysis of 123 Patients with Primary IgA Nephropathy

Objective:To study the relationship between clinical manifestation and pathological feature with primary IgA nephropathy.Methods:The clinical and pathological data of 123 patients with primary IgA nephropathy diagnosed by renal biopsy were retrospectively analyzed.Results:The incidence of 123 IgA nephropathy was the highest in patients at the age of 21～40 years (65.8%).Clinically,IgA nephropathy of the paroxysmal gross hematuria type was the most common among the patients(36.6%).The pathological type Ⅱ was the most common (56.1%) followed by type Ⅲ(20.3%).Pathological type was positively correlated with the clinical manifestations(P0.01).Serum creatinine,serum uric acid and blood lipid levels increased with Lee’s pathological grade increasing (P0.05).Conclusion:IgA nephropathy had diverse clinical manifestations.Histomorphology changed with different severity.Early renal biopsy should be performed and appropriate therapy administered.