Accuracy of panoramic radiographic predictor signs in the assessment of proximity of impacted third molars with the mandibular canal

OBJECTIVES: This study aimed to validate the accuracy of panoramic radiographic risk signs through detection of presence or absence of corticalization between an impacted mandibular third molar and the inferior alveolar canal on cone beam computed tomography (CBCT). METHODS: This retrospective study analyzed 210 impacted mandibular third molars from 135 patients (aged 17-51 years) who showed one or more of the seven previously established panoramic radiographic risk signs of inferior alveolar nerve exposure. These patients were referred for CBCT examination. Three-dimensional images were used to assess the canal position relative to the third molar, the proximity between the canal and third molar, and third molar angulation. The correlation of panoramic findings and CBCT was evaluated using a Chi-square test. RESULTS: Panoramic findings of interruption of inferior alveolar canal wall, isolated or combined with one of these signs (darkening of third molar roots, narrowing of canal, and diversion of canal); darkening of the roots; and narrowing of canal were significantly correlated with direct contact between the inferior alveolar canal and impacted third molars on CBCT (P < 0.001). CONCLUSION: Preoperative CBCT is recommended for cases showing interruption of canal wall; darkening of the roots or narrowing of the canal; or association between interruption and narrowing, diversion, or darkening of roots in a panoramic view. This study evaluated the risk relationship between the inferior alveolar nerve and impacted mandibular third molars, with the aim of reducing the occurrence of postoperative injury to the inferior alveolar nerve.