Discovery of Potential Antitubercular Activity in on-AntibioticsThrough Virtual Screening

Ligand based virtual screening is an extremely useful tool in identification of lead molecules, especially for less explored molecular targets [1]. Amongst many techniques available, 3D pharmacophore model based virtual screening methods are most successful [2]. Virtual screening of chemical libraries compiling known therapeutics has significantly helped in knowledge-based rational drug repositioning [3-6]. It has been recently recognized as an effective strategy to aid novel drug discovery for rare and neglected conditions [7-9].