乳腺癌
癌症研究
STAT1
化疗
生物
癌症
医学
肿瘤科
内科学
干扰素
免疫学
作者
Marie‐Emmanuelle Legrier,Ivan Bièche,Julie Gaston,Arnaud Beurdeley,Vanessa Yvonnet,Olivier Déas,Aurélie Thuleau,Sophie Château‐Joubert,Jean‐Luc Servely,Sophie Vacher,Myriam Lassalle,Stéphane Depil,Gordon C. Tucker,Jean‐Jacques Fontaine,Marie‐France Poupon,Sergio Roman‐Roman,Jean‐Gabriel Judde,Didier Decaudin,Stefano Cairo,Elisabetta Marangoni
摘要
Treatment-induced activation of the IFN/STAT1 pathway in tumour cells is associated with chemotherapy response in ER- breast cancer. Further validations in prospective clinical trials will aim to evaluate the usefulness of this signature to assist therapeutic strategies in the clinical setting.
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