信使核糖核酸
转染
化学
免疫系统
细胞生物学
细胞
基因表达
佐剂
基因传递
分子生物学
树突状细胞
两亲性
细胞培养
作者
Qi Wei,Ruoshui Li,Jiaqi Fan,Mengyuan Xu,Pengcheng Yuan,Jiwei Liu,Qian Wang,Youqing Shen,Nigel K. H. Slater,Jianbin Tang
摘要
. Furthermore, GL9 promoted dendritic cell maturation, highlighting its potential as an adjuvant for mRNA vaccines. Thus, GLs, which enhance both transfection and immune activation, were incorporated into five-component LNPs to establish a promising platform for mRNA vaccines and therapeutics, offering an innovative strategy to optimize LNP-mediated mRNA delivery.
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(2025-6-4)
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