痴呆
认知障碍
认知
可靠性(半导体)
认知评估系统
任务(项目管理)
心理学
认知障碍
认知功能衰退
认知测验
物理医学与康复
医学
诊断准确性
小型精神状态检查
执行职能
鉴定(生物学)
有效性
老年病科
记忆诊所
蒙特利尔认知评估
阿尔茨海默病
老年人
老年学
记忆障碍
听力学
阶段(地层学)
作者
Dong-ni Pan,Hailun Xie,Juejing Ren,Ji Shen,Jing Li,Yanjia Zeng,Wen Wang,Dingyao Fan,Gui Xue
摘要
INTRODUCTION: With the aging global population, effective screening tools for age-related cognitive disorders are urgently needed. Mild cognitive impairment (MCI), a transitional stage between normal aging and dementia, requires early detection for timely intervention. METHODS: The current research developed an innovative electronic assessment tool designed with three task modules targeting executive function, memory binding, and spatial navigation to quickly screen for MCI in older adults. A validation study was conducted with 271 older participants, aged 56 to 89, comprising 138 individuals with MCI and 133 cognitively normal controls. An independent dataset from a community hospital was used for further confirmation. RESULTS: The validation study indicated excellent reliability and validity, achieving 72% accuracy in distinguishing MCI from cognitively normal individuals, with excellent screening power (AUC = 0.807; 95% CI: 0.756-0.858). This performance surpasses that of the paper-and-pencil Mini-Mental State Examination (MMSE). The independent dataset from a community hospital further confirmed that the tool achieved a good accuracy rate of 93% (26/28) in predicting MCI. CONCLUSION: These results provide strong tool support for the early identification of MCI, enhancing the effective management of cognitive decline in at-risk elderly individuals.
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