生物分析
药代动力学
分析物
计算机科学
纳米技术
化学
药理学
医学
色谱法
材料科学
作者
Xiaolong Zhang,Linglong Zou,Weiping Shao,Zhongping John Lin
出处
期刊:Journal of Bioanalysis & Biomedicine
[OMICS Publishing Group]
日期:2020-01-01
卷期号:12 (3): 1-6
标识
DOI:10.37421/1948-593x.2020.12.227
摘要
Over the past ten years, the global market for large molecule therapeutics has rapidly grown for the treatment of a variety of diseases. LBA and LC-MS are two platforms widely used in pharmacokinetic bioanalysis. In this review, we compare LBA and LC-MS and summarize their strengths and limitations. Strategies for platform selection are provided according to the study purpose, study phase, analyte types, assay requirements and other factors.
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