脆弱类杆菌
克林霉素
青霉素
菌血症
微生物学
产气荚膜梭菌
阿莫西林
厌氧菌
甲硝唑
医学
克拉维酸
头孢西丁
拟杆菌
抗生素
哌拉西林
生物
细菌
铜绿假单胞菌
金黄色葡萄球菌
遗传学
作者
Jorge Ligero-López,Eduardo Rubio‐Mora,Mario Ruíz-Bastián,María Inmaculada Quiles-Melero,Juana Cacho-Calvo,Emilio Cendejas‐Bueno
出处
期刊:Anaerobe
[Elsevier BV]
日期:2023-11-19
卷期号:84: 102803-102803
被引量:5
标识
DOI:10.1016/j.anaerobe.2023.102803
摘要
Infections from anaerobic microorganisms result from breached mucosal barriers, posing a significant mortality risk. A retrospective study at Hospital Universitario La Paz (Madrid) from 2010 to 2022 analyzed 491 (6.17 %) anaerobic bacteremia cases out of 7956 significant bacteremia cases among 171,833 blood culture requests. Bacteroides fragilis was the most frequently isolated species (28.3 %), followed by Clostridium perfringens (13.6 %). B. fragilis showed good susceptibility to amoxicillin/ clavulanic acid (86 %), piperacillin/tazobactam (86 %), and metronidazole (87.7 %). In general, non-fragilis Bacteroides species showed low susceptibility to penicillin (7 %), amoxicillin (17.5 %), and clindamycin (64.9 %). Of our 13 non-perfringens Clostridium isolates, four exhibited resistance to penicillin and four showed resistance to clindamycin. Lactobacillus species were highly susceptible to antibiotics tested. Prevotella spp. showed low susceptibility to penicillin (20 %), amoxicillin (20 %), and clindamycin (40 %). The study contributes valuable data for monitoring and improving anaerobic bacteremia treatment.
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