Sulfoximine Aided Ru(II)-Catalyzed Asymmetric Double C(sp2)–H Hydroarylations of Olefins

Presented here is a sulfoximine-directed Ru(II)-catalyzed asymmetric intramolecular double C(sp²)-H hydroarylation of olefins. This process provides a diastereoselective and enantiospecific synthetic route to highly substituted tetrahydrobenzodifurans. Notably, the reaction accommodates labile functional groups and is scalable to gram quantities.